Preheat oven to 425°F and line a large sheet pan with parchment paper.
Peel head of cauliflower and break florets into small pieces.
In a large bowl combine cauliflower florets and olive oil. Toss to completely coat the cauliflower florets.
In the same bowl sprinkle the breadcrumbs, salt, pepper, granulated garlic powder, and onion powder on top. Toss again to fully coat the cauliflower florets.
Pour onto lined sheet pan and spread the cauliflower florets out in one layer.
Bake for 15 minutes, take the sheet pan out of the oven and flip the florets. Return to the oven and bake for an additional 15 minutes. Bake until the cauliflower florets are golden brown and slightly crispy.